Principal Investigator

Prof. Yu Xia
Yu Xia earned her B.S. (1999) in Chemistry from Lanzhou University, China, M.S. (2002) from Shanghai Institute of Material Medical, CASs, China, and Ph.D. (2006) under the supervision of Professor Scott A. McLuckey from Purdue University, USA. After postdoctoral training with Professor Graham R. Cooks at Purdue, Dr. Xia took positions as an Assistant and Associate Professor at the Department of Chemistry, Purdue University (2009-2017). She joined Tsinghua University as a Professor of the Department of Chemistry in 2016. She was the recipient of the ASMS Research Award and her research has been supported by the Distinguished Young Scholars and the Outstanding Young Scholars Program from the National Natural Science Foundation of China. She served as Secretary of the Board of Directors of the American Society for Mass Spectrometry from 2015 to 2017. She currently serves as Vice Chair of the Organic Analysis Committee of the Chinese Chemical Society, Vice President of the International Lipidomics Society (ILS), Asia-Pacific Regional Reprsentative, Exuctive Board of the International Mass Spectrometry Foundation (IMSF), Editor of Journal of Mass Spectrometry, and Editorial Board Member of Journal of Lipid Research. She teaches multiple undergraduate and graduate courses and has received the First Prize for Outstanding Class Advisor and the Excellent Mentor Award at Tsinghua University.
瑕瑜课题组-成员 Xia Lab-成员
Postdoctoral Researcher

Dr. Haiyue Hou
2016.9–2020.6 B.S. College of Chemistry, Beijing University of Chemical Technology
2020.9–2025.6 Ph.D. College of Chemistry, Beijing University of Chemical Technology
2025.7–now, Postdoc, Department of Chemistry, Tsinghua University
Awards
2025 Outstanding Graduate Student of Beijing City
2024 Graduate Fellowship of BUCT
Representative Work:
· Haiyue Hou, Shuya Yang, Xuexin Yang, Zhenxia Du*, et al. Comprehensive profiling and development of a collision cross section database for milk oligosaccharides via orthogonal UPLC-cyclic ion mobility-mass spectrometry system. Food Chem., 2025, 480.
· Haiyue Hou, Shuya Yang, Xuexin Yang, Zhenxia Du*, et al. Sensitive and high-throughput isomer-specific analysis of human milk oligosaccharides using UPLC-MS/MS and its application to secretor status assignment. Carbohydr. Polym., 2025, 352.
· Haiyue Hou, Mengyu Wang, Shuya Yang, Zhenxia Du*, et al. Evaluation of Prebiotic Glycan Composition in Human Milk and Infant Formula: Profile of Galacto-Oligosaccharides and Absolute Quantification of Major Milk Oligosaccharides by UPLC-Cyclic IM-MS and UPLC-MS/MS. J. Agric. Food Chem., 2024.
Research interests:
The selective enrichment and analysis of glycosphingolipids;
Isomer-resolved charaterization of human milk oligosaccharides (Ph.D)
瑕瑜课题组-成员 Xia Lab-成员
Graduate Students

Lipeng Qiao
2018.9-2022.6 B.S. College of Chemistry, Chemical Engineering and Materials Science, Soochow University
2022.9-now Department of Chemistry, Tsinghua University
瑕瑜课题组-成员 Xia Lab-成员

Wei Wan
2019.9-2023.6 B.S. College of Chemistry, Sichuan University
2023.9-now Department of Chemistry, Tsinghua University
瑕瑜课题组-成员 Xia Lab-成员

Jitong Wang
2019.8-2023.6 B.S. in Chemical biology, Department of Chemistry, Tsinghua University
2023.9-now Department of Chemistry, Tsinghua University
瑕瑜课题组-成员 Xia Lab-成员

Tengyuan Miao
2020.8-2024.6 B.S. College of Chemistry and Chemical Engineering, Hunan University
2024.8-now Department of Chemistry, Tsinghua University
瑕瑜课题组-成员 Xia Lab-成员

Zhihui Huang
2020.09 – 2024.06 B.S. College of Chemistry and Molecular Sciences, Wuhan University
2025.08 – now Department of Chemistry, Tsinghua University
Award:
2024:Tsinghua University Future Scholar Fellowship for Doctoral Students
2025:Second-Class Prize for Comprehensive Excellence
Representative Work:
· Yongyi Li, Qian An, Zhihui Huang, et al. Surface Plasmon Polariton Enable Reaction-Specific Energy Transduction for Molecular Ionization. Laser & Photonics Reviews. 2026.
· Zhongxian Li, Liwei Wang, Zhihui Huang, et al. Cross-Double Deoxygenative Carbon−Carbon Bond Formationbetween Benzyl Benzoates and Allylic Alcohols. ACS Catal. 2024, 14, 12, 9496–9504.
瑕瑜课题组-成员 Xia Lab-成员

Yongle Chen
2016.9-2020.6 B.S. West China School of Pharmacy, Sichuan University
2020.9-2023.6 M.S. Academy of Military Medical Sciences - National Center for Protein Sciences (Beijing)
2023.10-now: Department of Chemistry, Tsinghua University
瑕瑜课题组-成员 Xia Lab-成员

Weishen Zhou
2021.8-2025.6 B.S. College of Chemistry, JiLin University
2025.8-now Department of Chemistry, Tsinghua University
Representative Work:
· Weishen Zhou, Songrui Li, Hetong Wang, Huifeng Zhang, Qiong Jia*. Novel zinc nanoclusters based ratiometric fluorescence sensing strategy for sensitive detection of thiram. Food Chem. 2026, 505, 147957.
· Zhou Weishen, Jia Jiahao, Mo Kangqiang, Xue Yingke, Li Songrui, Jia Qiong*. Application Progress of Metal Nanoclusters in Detection of Pesticides. Chin. J. Anal. Chem., 2024, 52, 460-468.
瑕瑜课题组-成员 Xia Lab-成员

Minmin Hu
2018.9-2022.6 B.S. China University of Mining & Technology, Beijing
2022.9-2025.6 M.S. Beijing Normal University
2026.4-now Department of Chemistry, Tsinghua University
Representative Work:
C.Yang, M.Hu, C.Hu, X.Mi, S.Luo. Visible Light Promoted de Mayo Type Reaction of Bicyclo[1.1.0]butanes. Chem. Eur. J.2024, 30, e202402965.
J.Gao, M.Hu, X.Mi. Transition-Metal-Free Direct α-Arylation of Weinreb-type Amides with Arylboronic Acids through Aza-oxyallyl Cation Intermediates. J. Org. Chem. 2024, 89, 18, 13730–13734.